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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 322678Generated: October 26, 2026

p-Tolylacetic acid → N-[(4-methylphenyl)acetyl]alanine iso-butyl ester

https://huagongshe.com/reaction/322678

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-Tolylacetic acidHCID 248474—
Reactant2-methylpropyl (2S)-2-aminopropanoateHCID 13743556—
ProductN-[(4-methylphenyl)acetyl]alanine iso-butyl esterHCID 53936136—

Reaction Steps

Following General Procedure I′ above, and using 4-methylphenylacetic acid (Aldrich) and L-alanine iso-butyl ester (prepared following General Procedure J′ above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06211235B1
Source datasetuspto-grants-2001_04
ORD IDord-4dff4e5350584ffdb69222e9efad8170
Source noteuspto-grants-2001_04