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HRID322734

反应详情

EQUATION

反应方程式

HRID 322734 的结构方程式

REACTANTS

反应物

4
结构：COC(=O)[C@@H](N)Cc1ccccc1.Cl
HCID75736

Methyl L-phenylalaninate hydrochloride (1:1)

C10H14ClNO2

结构：C[C@H](NC(=O)OC(C)(C)C)C(=O)O
HCID85082

L-Alanine, N-[(1,1-dimethylethoxy)carbonyl]-

C8H15NO4

结构：O=C(O)CC1CC1
HCID138440

Cyclopropaneacetic acid

C5H8O2

结构：COC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](C)N
HCID12988705

未命名化合物

PRODUCTS

生成物

1
结构：COC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](C)NC(=O)CC1CC1
HCID22895032

未命名化合物

PROCEDURE

实验过程

Following General Procedure U and using cyclopropylacetic acid (Lancaster) and N-(L-alaninyl)-L-phenylalanine methyl ester (prepared by coupling N-BOC-L-alanine (Bachem) with L-phenylalanine methyl ester hydrochloride (Bachem) using General Procedure U, followed by removal of the BOC-group using General Procedure Y), the title compound was prepared as a solid (mp=128-131° C.). The reaction was monitored by tlc (Rf=0.14 in 1:1 EtOAc/hexanes).

WORKUP

后处理

  1. customprepared
  2. customfollowed by removal of the BOC-group
  3. customwas prepared as a solid (mp=128-131° C.)