Methyl valinate hydrochloride → HCID 22894901, compound

HRID 322763Notes

Reaction equation

HRID 322763 reaction equation
[F:1][C:2]1[CH:3]=[C:4]([CH2:9][C:10]([NH:12][C@H:13]([C:15]([OH:17])=O)[CH3:14])=[O:11])[CH:5]=[C:6]([F:8])[CH:7]=1.Cl.[CH3:19][O:20][C:21](=[O:27])[C@H:22]([CH:24]([CH3:26])[CH3:25])[NH2:23]>>[CH3:19][O:20][C:21](=[O:27])[C@H:22]([CH:24]([CH3:26])[CH3:25])[NH:23][C:15](=[O:17])[C@H:13]([CH3:14])[NH:12][C:10](=[O:11])[CH2:9][C:4]1[CH:5]=[C:6]([F:8])[CH:7]=[C:2]([F:1])[CH:3]=1

Participants

3

Reactant 2

HCID 111190Methyl valinate hydrochlorideHCID 12135350(2S)-2-[[2-(3,5-difluorophenyl)acetyl]amino]propanoic acid

Product 1

HCID 22894901HCID 22894901, compound

Procedure

Following General Procedure C and using N-(3,5-difluorophenylacetyl)-L-alanine (from Example B2 above) and L-valine methyl ester hydrochloride (Aldrich), the title compound was prepared as a solid.

Sources & evidence

ORD record
ord-bb14e59e7e824523b6a5a38664a7e2c4
Source dataset
uspto-grants-2001_04
Patent number
US06211235B1

Reaction notes

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