Glycine methyl ester hydrochloride → HCID 9817091, compound

HRID 322780Notes

Reaction equation

HRID 322780 reaction equation
[C:1]1([CH2:7][C:8]([NH:10][C@H:11]([C:13]([OH:15])=O)[CH3:12])=[O:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.Cl.[CH3:17][O:18][C:19](=[O:22])[CH2:20][NH2:21]>>[CH3:17][O:18][C:19](=[O:22])[CH2:20][NH:21][C:13](=[O:15])[C@H:11]([CH3:12])[NH:10][C:8](=[O:9])[CH2:7][C:1]1[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

Participants

3

Reactant 2

HCID 122755Glycine methyl ester hydrochlorideHCID 7004640N-(Phenylacetyl)-L-alanine

Product 1

HCID 9817091HCID 9817091, compound

Procedure

Following General Procedure A and using N-(phenylacetyl)-L-alanine (from Example B1 above) and glycine methyl ester hydrochloride (Aldrich), the title compound was prepared as a solid (mp=152-153.5° C.). The reaction was monitored by tlc (Rf=0.10 in 50% EtOAc/hexanes).

Sources & evidence

ORD record
ord-89b97b2382d44a3b9adf12485b0f593d
Source dataset
uspto-grants-2001_04
Patent number
US06211235B1

Reaction notes

Loading…