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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 322832Generated: October 30, 2026

4-Pentynoic acid → HCID 18362936, compound

https://huagongshe.com/reaction/322832

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Pentynoic acidHCID 22464—
ReactantN,N-Bis(trimethylsilyl)trifluoroacetamideHCID 65279—
ReactantHCID 18362930HCID 18362930—
ProductHCID 18362936HCID 18362936—

Reaction Steps

The sub-title compound was prepared from 5-iodo-3-methyl-1-(2-methylpropyl)-6-(1-naphthalenylmethyl)-1H-pyrrolo[3,4-d]pyrimidine-2,4(3H,6H)-dione, and 4-pentynoic acid in the presence of bistrimethylsilyltrifluoroacetamide in a manner analogous to the method of Example 13 above.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06211368B1
Source datasetuspto-grants-2001_04
ORD IDord-f02c71f859304fdbbdd9a2f2f91ce90d
Source noteuspto-grants-2001_04