反应详情

A solution of methyl (RS)-5-[3-(3-nitro-benzyloxy)phenyl]-5-oxo-4-(2-methylphenyl)pentanoate (1.2 g) in methyl acetate (30 mL) is treated with palladium on carbon catalyst (5%; 200 mg) and shaken under hydrogen at atmospheric pressure and room temperature for 3 hours. The mixture is filtered and evaporated giving methyl (RS)-5-[3-(3-aminobenzyloxy)- phenyl]-5-oxo-4-(2-methylphenyl)pentanoate (1.3 g) in the form of a brown oil.

1. filtrationThe mixture is filtered
2. customevaporated