Methyl 4-(benzyloxy)-2-hydroxybenzoate → Methyl 2-hydroxy-4-(3-phenylpropyloxy)benzoate

Participants

Role	Name	HCID	Charge
Reactant	Methyl 4-(benzyloxy)-2-hydroxybenzoate	HCID 225489	—
Reactant	Methyl 2-hydroxy-4-(4-isopropylbenzyloxy)benzoate	HCID 10494455	—
Reactant	Methyl 2-hydroxy-4-(3,4-methylenedioxybenzyloxy)benzoate	HCID 10518444	—
Reactant	Benzoic acid, 2-hydroxy-4-[(4-methoxyphenyl)methoxy]-, methyl ester	HCID 10541338	—
Reactant	Methyl 2-hydroxy-4-(3-methoxybenzyloxy)benzoate	HCID 10660986	—
Reactant	Methyl 2-hydroxy-4-(2-(3-indolyl)ethoxy)benzoate	HCID 10686460	—
Reactant	Methyl 2-hydroxy-4-(2-phenylethoxy)benzoate	HCID 10707316	—
Reactant	Methyl 2-hydroxy-4-(1-naphthylmethoxy)benzoate	HCID 10757179	—
Reactant	Methyl 2-hydroxy-4-(4-nitrobenzyloxy)benzoate	HCID 22010125	—
Reactant	Methyl 2-hydroxy-4-(4-fluorobenzyloxy)benzoate	HCID 22010297	—
Reactant	Methyl 2-hydroxy-4-(2-naphthylmethoxy)benzoate	HCID 22010402	—
Reactant	Methyl 2-hydroxy-4-(3,4-dichlorobenzyloxy)benzoate	HCID 22010505	—
Product	Methyl 2-hydroxy-4-(3-phenylpropyloxy)benzoate	HCID 22010383	—

Reaction Steps

methyl 2-hydroxy-4-(2-(3-indolyl)ethoxy)benzoate; methyl 2-hydroxy-4-benzyloxybenzoate, m.p. 101-102° C.; methyl 2-hydroxy-4-(2-naphthylmethoxy)benzoate; methyl 2-hydroxy-4-(1-naphthylmethoxy)benzoate; methyl 2-hydroxy-4-(3,4-methylenedioxybenzyloxy)benzoate (solid); methyl 2-hydroxy-4-(2-phenylethoxy)benzoate; methyl 2-hydroxy-4-(4-isopropylbenzyloxy)benzoate, m.p. 68-70° C.; methyl 2-hydroxy-4-(4-nitrobenzyloxy)benzoate, m.p. 178-180° C.; methyl 2-hydroxy-4-(4-fluorobenzyloxy)benzoate, m.p. 82-84° C.; methyl 2-hydroxy-4-(3,4-dichlorobenzyloxy)benzoate, m.p. 134-136° C.; methyl 2-hydroxy-4-(4-methoxybenzyloxy)benzoate; and methyl 2-hydroxy-4-(3-methoxybenzyloxy)benzoate.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US06211234B1
Source dataset	uspto-grants-2001_04
ORD ID	ord-f31230f8a10e419eabc3bf200a4fff20
Source note	uspto-grants-2001_04