HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 322924Generated: October 27, 2026
Oxalyl chloride → 4-Benzyloxy-2-(1-o-tolylethoxy)benzoyl chloride
https://huagongshe.com/reaction/322924
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Oxalyl chloride | HCID 65578 | — |
| Reactant | 4-Benzyloxy-2-(1-o-tolylethoxy)benzoic acid | HCID 22010490 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 4-Benzyloxy-2-(1-o-tolylethoxy)benzoyl chloride | HCID 22010417 | — |
Reaction Steps
A solution of 4-benzyloxy-2-(1-o-tolylethoxy)benzoic acid (2.5 g) in dichloromethane (50 mL) is treated with a 2 M solution of oxalyl chloride in dichloromethane (6.5 mL) and stirred at 25° C. for 3.5 hours. The mixture is evaporated to give 4-benzyloxy-2-(1-o-tolylethoxy)benzoyl chloride as a brown liquid (2.73 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US06211234B1 |
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| Source dataset | uspto-grants-2001_04 |
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| ORD ID | ord-f7b6dee8fca34d0d9d4e838efb94ef69 |
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| Source note | uspto-grants-2001_04 |
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