HRID32293

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CCN(CC)CCNC(=O)c1cc(I)c(NS(C)(=O)=O)cc1OC

HCID16748091

未命名化合物

PRODUCTS

生成物

结构：CCN(CC)CCNC(=O)c1cc(I)c(NC(=O)c2ccc3c(c2)OCO3)cc1OC

HCID24828617

未命名化合物

PROCEDURE

实验过程

Produced analogously are: N-(2-diethylamino-ethyl)-5-iodo-2-methoxy-4-propionylylamino-benzamide; N-(2-diethylamino-ethyl)-4-(2,2-dimethyl-propionylamino)-5-iodo-2-methoxy-benzamide; N-(2-diethylamino-ethyl)-4-(2-hydroxy-acetylamino)-5-iodo-2-methoxy-benzamide; N-(2-diethylamino-ethyl)-4-(3-hydroxy-propionylamino)-5-iodo-2-methoxy-benzamide; N-(2-diethylamino-ethyl)-4-{2-[(2-hydroxy-ethyl)-methyl-amino]-acetylamino}-5-iodo-2-methoxy-benzamide; N-(2-diethylamino-ethyl)-5-iodo-2-methoxy-4-(2-morpholin-4-yl-acetylamino)-benzamide; 4-hydroxy-1-methyl-pyrrolidine-2-carboxylic acid [4-(2-diethylamino-ethylcarbamoyl)-2-iodo-5-methoxy-phenyl]-amide; N-(2-diethylamino-ethyl)-5-iodo-4-methanesulfonylamino-2-methoxy-benzamide; N-(2-diethylamino-ethyl)-5-iodo-4-butanesulfonylamino-2-methoxy-benzamide; N-(2-diethylamino-ethyl)-4-carboxy-acetylamino-5-iodo-2-methoxy-benzamide.

WORKUP

后处理

customProduced analogously

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-1c3e0b60773149feb8507a479f6936d3
来源数据集: uspto-grants-2008_09
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07427390B2
来源说明: uspto-grants-2008_09

反应 SMILES

[CH2:1]([N:3]([CH2:25][CH3:26])[CH2:4][CH2:5][NH:6][C:7](=[O:24])[C:8]1[CH:13]=[C:12]([I:14])[C:11]([NH:15][C:16](=[O:21])[C:17]([CH3:20])(C)[CH3:18])=[CH:10][C:9]=1[O:22][CH3:23])[CH3:2].C(N(CC)CCNC(=O)C1C=C(I)[C:37](NC(=O)CO)=[CH:36][C:35]=1[O:46][CH3:47])C.C(N(CC)CCNC(=O)C1C=C(I)C(NC(=O)CC[OH:69])=CC=1OC)C.C(N(CC)CCNC(=O)C1C=C(I)C(NC(=O)CN(CCO)C)=CC=1OC)C.C(N(CC)CCNC(=O)C1C=C(I)C(NC(=O)CN2CCOCC2)=CC=1OC)C.C(N(CC)CCNC(C1C(OC)=CC(NC(C2CC(O)CN2C)=O)=C(I)C=1)=O)C.C(N(CC)CCNC(=O)C1C=C(I)C(NS(C)(=O)=O)=CC=1OC)C.C(N(CC)CCNC(=O)C1C=C(I)C(NS(CCCC)(=O)=O)=CC=1OC)C.C(N(CC)CCNC(=O)C1C=C(I)C(C(O)=O)=C(NC(=O)C)C=1OC)C>>[CH2:1]([N:3]([CH2:25][CH3:26])[CH2:4][CH2:5][NH:6][C:7]([C:8]1[C:9]([O:22][CH3:23])=[CH:10][C:11]([NH:15][C:16]([C:17]2[CH:20]=[CH:37][C:36]3[O:69][CH2:47][O:46][C:35]=3[CH:18]=2)=[O:21])=[C:12]([I:14])[CH:13]=1)=[O:24])[CH3:2]