HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → sodium (RS)-4-(2,3-dimethylphenyl)-4-hydroxybutanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | ethyl (RS)-4-(2,3-dimethylphenyl)-4-hydroxybutanoate | HCID 53823409 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | sodium (RS)-4-(2,3-dimethylphenyl)-4-hydroxybutanoate | HCID 86756590 | — |
Reaction Steps
A solution of ethyl (RS)-4-(2,3-dimethylphenyl)-4-hydroxybutanoate (3.66 g) in ethanol (100 mL) is treated with 1 N sodium hydroxide solution (15.5 mL). The reaction mixture is stirred at room temperature for 18 hours, evaporated and the residue azeotroped with toluene to give sodium (RS)-4-(2,3-dimethylphenyl)-4-hydroxy-butanoate (3.2 g) as a brown solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06211234B1 |
| Source dataset | uspto-grants-2001_04 |
| ORD ID | ord-c806af179c854ef88b2716c8212b475c |
| Source note | uspto-grants-2001_04 |