Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ethylene Glycol → 1,3-Dioxolane, 2-(2-bromo-5-methoxyphenyl)-
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ethylene Glycol | HCID 174 | — |
| 반응물 | 2-Bromo-5-methoxybenzaldehyde | HCID 344480 | — |
| 촉매 | p-Toluenesulfonic acid | HCID 6101 | — |
| 용매 | Toluene | HCID 1140 | — |
| 생성물 | 1,3-Dioxolane, 2-(2-bromo-5-methoxyphenyl)- | HCID 11184503 | 95.2% |
반응 단계
A mixture of 2-bromo-5-methoxy-benzaldehyde (45.25 g), ethylene glycol (52.22 g) and 4-toluenesulphonic acid (0.4 g) in toluene (400 mL) is heated at reflux for 5 hours using a Dean and Stark apparatus to remove water formed in the reaction. The reaction mixture is washed five times with water (500 mL) and evaporated giving 2-(2-bromo-5-methoxyphenyl)-[1,3]dioxolane (51.9 g) as a yellow liquid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06211234B1 |
| 출처 데이터셋 | uspto-grants-2001_04 |
| ORD ID | ord-91ceb5c666b84da69273f6e9dc96427a |
| 출처 메모 | uspto-grants-2001_04 |