Azido(trimethyl)stannane → HCID 178423717, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 4-(4′-methylbiphenyl-2-carboxamido)-N-methyl-N-(2-cyanophenyl)benzamide (350 mg) and trimethyltin azide (453 mg) in xylene (15 ml) heated at 120° C. for 2 days and cooled to ambient temperature. The solution was directly applied to silica gel column (the column was pre-packed with chloroform as a solvent). The column was eluted with 2% methanol in chloroform and the solvent was evaporated in vacuo. The residue was solidified with diethyl ether to give 4-(4′-methylbiphenyl-2-carboxamido)-N-methyl-N-[2-(tetrazol-5-yl)phenyl]benzamide (233 mg) as a white powder.

Provenance & Evidence