Tecastemizole → HCID 9851964, compound

Participants

Reaction Steps

Prepare by the method of Example 2.6 using 1-benzyl-3-(phenylmethyl)-3-(2-methanesulfonyloxyethyl)-2-oxopyrrolidine (0.99 g, 2.6 mmol) and (1-(4-fluorobenzyl)-1H-benzimidazol-2-yl)(piperidin-4-yl)amine (0.80 g, 2.6 mmol) to give the title compound: Rf=0.22 (silica gel, 5% methanol/ethyl acetate/2% triethylamine).

Provenance & Evidence