HCID 18464600, compound → HCID 18464694, compound

HRID 323299Notes

Reaction equation

HRID 323299 reaction equation
S(O[CH2:6][C:7]1[CH:12]=[CH:11][C:10]([O:13][CH3:14])=[CH:9][CH:8]=1)(=O)(=O)C.[CH3:15][O:16][C:17]1[CH:18]=[C:19]([CH:37]=[C:38]([O:42][CH3:43])[C:39]=1[O:40][CH3:41])[CH2:20][N:21]1[CH2:25][CH2:24][CH:23]([CH2:26][CH2:27][O:28][Si:29]([C:32]([CH3:35])([CH3:34])[CH3:33])([CH3:31])[CH3:30])[C:22]1=[O:36]>>[CH3:15][O:16][C:17]1[CH:18]=[C:19]([CH:37]=[C:38]([O:42][CH3:43])[C:39]=1[O:40][CH3:41])[CH2:20][N:21]1[CH2:25][CH2:24][C:23]([CH2:6][C:7]2[CH:12]=[CH:11][C:10]([O:13][CH3:14])=[CH:9][CH:8]=2)([CH2:26][CH2:27][O:28][Si:29]([C:32]([CH3:35])([CH3:34])[CH3:33])([CH3:31])[CH3:30])[C:22]1=[O:36]

Participants

3

Reactant 2

HCID 18464600HCID 18464600, compoundHCID 18464680HCID 18464680, compound

Product 1

HCID 18464694HCID 18464694, compound

Procedure

Prepare by the method of Example 17.3 using 4-methoxybenzyl mesylate and 1-(3,4,5-trimethoxybenzyl)-3-(2-(t-butyldimethylsilyloxy)ethyl)-2-oxopyrrolidine to give the title compound: Rf=0.15 (silica gel, 1/4 ethyl acetate/hexane).

Sources & evidence

ORD record
ord-174ead7d403043abad9f93e1022b185e
Source dataset
uspto-grants-2001_04
Patent number
US06211199B1

Reaction notes

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