HuagongsheHuagongshe Chemistry Print Report · For research reference only
Oxalyl chloride → 2-Methoxy-5-(1H-tetrazol-1-yl)benzoyl Chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Oxalyl chloride | HCID 65578 | — |
| Reactant | 2-methoxy-5-(1H-tetrazol-1-yl)benzoic acid | HCID 18464435 | — |
| Catalyst | Dimethylformamide | HCID 6228 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 2-Methoxy-5-(1H-tetrazol-1-yl)benzoyl Chloride | HCID 15392022 | — |
Reaction Steps
Combine 2-methoxy-5-(1H-tetrazol-1-yl)benzoic acid (1.2 g, 5.5 mmol) and dichloromethane (40 mL). Add dropwise oxalyl chloride (0.72 mL, 8.25 mmol) followed by dimethylformamide (3 drops). After 4 hours, evaporate in vacuo and dry to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06211199B1 |
| Source dataset | uspto-grants-2001_04 |
| ORD ID | ord-71c33eac621b4ede997e635f4d3830cc |
| Source note | uspto-grants-2001_04 |