反应详情

Combine methyl 2-methoxy-5-methylsulfonylbenzoate (2.24 g, 9.2 mmol) and a 1 M aqueous potassium hydroxide solution (10 mL, 10 mmol). Heat to reflux. After 2 hours, filter while still hot, cool in an ice bath, and acidify by dropwise addition of a 1 M aqueous hydrochloric acid solution (11 mL) to give a solid. Collect the solid by filtration, rinse with water, and dry to give the title compound.

1. temperatureHeat to reflux
2. filtrationfilter while still hot,
3. temperaturecool in an ice bath
4. additionacidify by dropwise addition of a 1 M aqueous hydrochloric acid solution (11 mL)
5. customto give a solid
6. customCollect the solid
7. filtrationby filtration
8. washrinse with water
9. customdry