(1-(2-ethoxyethyl)-1H-benzimidazol-2-yl)(piperidin-4-yl)amine → HCID 20642269, compound

HRID 323404Notes

Reaction equation

HRID 323404 reaction equation
[CH2:1]([O:3][CH2:4][CH2:5][N:6]1[C:10]2[CH:11]=[CH:12][CH:13]=[CH:14][C:9]=2[N:8]=[C:7]1[NH:15][CH:16]1[CH2:21][CH2:20][NH:19][CH2:18][CH2:17]1)[CH3:2].[C:22]([N:30]1[CH2:34][CH2:33][C:32]([C:42]2[CH:47]=[CH:46][CH:45]=[CH:44][CH:43]=2)([CH2:35][CH2:36]OS(C)(=O)=O)[CH2:31]1)(=[O:29])[C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1>>[C:22]([N:30]1[CH2:34][CH2:33][C:32]([CH2:35][CH2:36][N:19]2[CH2:18][CH2:17][CH:16]([NH:15][C:7]3[N:6]([CH2:5][CH2:4][O:3][CH2:1][CH3:2])[C:10]4[CH:11]=[CH:12][CH:13]=[CH:14][C:9]=4[N:8]=3)[CH2:21][CH2:20]2)([C:42]2[CH:47]=[CH:46][CH:45]=[CH:44][CH:43]=2)[CH2:31]1)(=[O:29])[C:23]1[CH:24]=[CH:25][CH:26]=[CH:27][CH:28]=1

Participants

3

Reactant 2

HCID 13808350(1-(2-ethoxyethyl)-1H-benzimidazol-2-yl)(piperidin-4-yl)amineHCID 18464490HCID 18464490, compound

Product 1

HCID 20642269HCID 20642269, compound

Procedure

Prepare by the method of Example 1.6 using (1-(2-ethyoxyethyl)-1H-benzimidazol-2-yl)(piperidin-4-yl)amine and 1-benzoyl-3-phenyl-3-(2-methanesulfonyloxyethyl)pyrrolidine to give the title compound.

Sources & evidence

ORD record
ord-60414cf8327d499585709964bbc190ad
Source dataset
uspto-grants-2001_04
Patent number
US06211199B1

Reaction notes

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