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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 323440Generated: October 30, 2026

(1-(2-ethoxyethyl)-1H-benzimidazol-2-yl)(piperidin-4-yl)amine → HCID 54072475, compound

https://huagongshe.com/reaction/323440

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(1-(2-ethoxyethyl)-1H-benzimidazol-2-yl)(piperidin-4-yl)amineHCID 13808350—
ReactantHCID 54560292HCID 54560292—
ProductHCID 54072475HCID 54072475—

Reaction Steps

Prepare by the method of Example 1.6 using 1-((S)-α-methylbenzyl)-3-(4-fluorophenylmethyl)-3-(2-methanesulfonyloxyethyl)-2-oxopyrrolidine (Rf=0.59 silica gel, ethyl acetate) (0.67 g, 1.59 mmol) and (1-(2-ethoxyethyl)-1H-benzimidazol-2-yl)(piperidin-4-yl)amine to give a diastereomer of the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06211199B1
Source datasetuspto-grants-2001_04
ORD IDord-732d57ce4cfe4568b5b87c2499c9c875
Source noteuspto-grants-2001_04