Chloroacetic Acid → HCID 86756603, compound

Participants

Reaction Steps

Aqueous solution of sodium hydroxide 17.66 g (0.44 mol) in 30 ml of water was added drop by drop to the mixture of 2,4,6-trimercapto-1,3,4-triazine 23.0 g (0.13 mol), chloroacetic acid 54.0 g (0.44 mol) and ethanol 300 ml with stirring at room temperature. After 20 minutes it was heated to 50° C., and aqueous solution of sodium hydroxide 17.6 g (0.44 mol) in 30 ml of water was added drop by drop slowly. It was cooled off to room temperature after 3 hours stirring at 50° C., and then water was added till reaction liquid became uniform, and hydrochloric acid was added for neutralization. Resulted crystal was filtrated and recrystallized in methanol to obtain 2,4,6 tris-carboxymethylthio-1,3,4-triazine in amount of 35.4 g (0.10 mol). Yield 76%.

Provenance & Evidence