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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 323948Generated: October 25, 2026

N-[1-(4'-Benzyloxybiphenyl-4-yl)-1-methylethyl]-3-(imidazol-1-yl)propylamine → 4'-{1-[3-(Imidazol-1-yl)propylamino]-1-methylethyl}biphenyl-4-ol

https://huagongshe.com/reaction/323948

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-[1-(4'-Benzyloxybiphenyl-4-yl)-1-methylethyl]-3-(imidazol-1-yl)propylamineHCID 18349622—
CatalystPalladiumHCID 23938—
Product4'-{1-[3-(Imidazol-1-yl)propylamino]-1-methylethyl}biphenyl-4-olHCID 18349596—

Reaction Steps

N-[1-(4′-Benzyloxybiphenyl-4-yl)-1-methylethyl]-3-(imidazol-1-yl)propylamine was hydrogenated, using palladium on charcoal as catalyst, in IMS at atmospheric pressure to give 4′-{1-[3-(imidazol-1-yl)propylamino]-1-methylethyl}biphenyl-4-ol, m.p. 178-180° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06215001B1
Source datasetuspto-grants-2001_04
ORD IDord-7f7b9d0022a945518db9be7e6ecca4ec
Source noteuspto-grants-2001_04