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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 323976Generated: October 29, 2026

4-Cyanophenol → HCID 532712, compound

https://huagongshe.com/reaction/323976

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-CyanophenolHCID 13019—
ReactantValeryl chlorideHCID 61186—
SolventTriethylamineHCID 8471—
ProductHCID 532712HCID 532712—

Reaction Steps

This compound was prepared by reacting 4-hydroxybenzonitrile with valeryl chloride in the presence of triethylamine to give 4-cyanophenyl valerate which was subjected to a Fries rearrangement with aluminium chloride to give 4-hydroxy-3-valerylbenzonitrile which was reduced with sodium borohydride to give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06215001B1
Source datasetuspto-grants-2001_04
ORD IDord-756e263eecda4e77835584bb6fb72301
Source noteuspto-grants-2001_04