3-Methyl-1H-indole-6-carboxylic acid → 4-{(R)-2-[(3-Methyl-1H-indole-6-carbonyl)amino]-2-phenyl-ethoxymethyl}piperidine-1-carboxylic acid tert-butyl ester

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Reaction Steps

Using coupling method A, 4-[(R)-2-amino-2-phenylethoxy-methyl)piperidine-1-carboxylic acid tert-butyl ester (1 g, 3.0 mmol) and 3-methylindole-6-carboxylic acid (0.54 g, 3.0 mmol) afforded the title compound as a crude residue, which was used without further purification.

Provenance & Evidence