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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 323990Generated: October 26, 2026

1H-Imidazole-1-propanal → N-[1-(4'-Benzyloxybiphenyl-4-yl)-1-methylethyl]-3-(imidazol-1-yl)propylamine

https://huagongshe.com/reaction/323990

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1H-Imidazole-1-propanalHCID 4712274—
Reactant1-(4'-Benzyloxybiphenyl-4-yl)-1-methylethylamineHCID 18349650—
ProductN-[1-(4'-Benzyloxybiphenyl-4-yl)-1-methylethyl]-3-(imidazol-1-yl)propylamineHCID 18349622—

Reaction Steps

In a similar manner to Example 24, 1-(4′-benzyloxybiphenyl-4-yl)-1-methylethylamine (A15) (1.4 g) and 3-(imidazol-1-yl)propionaldehyde (0.72 g) were reacted to give N-[1-(4′-benzyloxybiphenyl-4-yl)-1-methylethyl)-3-(imidazol-1-yl)propylamine, m.p. 93-95° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06215001B1
Source datasetuspto-grants-2001_04
ORD IDord-19a35c7cbf184c42a1231e2102a65809
Source noteuspto-grants-2001_04