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HRID32402

反应详情

EQUATION

反应方程式

HRID 32402 的结构方程式

REACTANTS

反应物

2
结构：O=C(O)c1cc2cc(Cl)ccc2[nH]1
HCID82693

5-Chloroindole-2-carboxylate

C9H6ClNO2

结构：CC(C)(C)OC(=O)N1CCC(COCC(N)c2ccccc2Cl)CC1
HCID69309645

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)(C)OC(=O)N1CCC(COCC(NC(=O)c2cc3cc(Cl)ccc3[nH]2)c2ccccc2Cl)CC1
HCID69307917

未命名化合物

PROCEDURE

实验过程

Using coupling method A, 4-[2-amino-2-(2-chlorophenyl)-ethoxymethyl]piperidine-1-carboxylic acid tert-butyl ester (300 mg, 0.8 mmol) and 5-chloroindole-2-carboxylic acid (158 mg, 1.4 mmol) afforded, after purification (SiO2: 33% EtOAc in hexane), 407 mg (92%) of the title compound.

WORKUP

后处理

  1. customafforded
  2. customafter purification (SiO2: 33% EtOAc in hexane), 407 mg (92%) of the title compound