HRID32404

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID15543042

未命名化合物

结构：CC(C)(C)OC(=O)N1CCC(COCC(N)c2ccccc2F)CC1

HCID69308093

未命名化合物

PRODUCTS

生成物

结构：CC(C)(C)OC(=O)N1CCC(COCC(NC(=O)c2ccc3c(Cl)c[nH]c3c2)c2ccccc2F)CC1

HCID69310706

未命名化合物

PROCEDURE

实验过程

Using coupling method A, 4-[2-amino-2-(2-fluorophenyl)-ethoxymethyl]piperidine-1-carboxylic acid tert-butyl ester (600 mg, 1.7 mmol) and 3-chloroindole-6-carboxylic acid (367 mg, 1.9 mmol) afforded, after purification (SiO2: 10 DCM: 2 EtOAc: 2 Hexane: 0 to 0.125 isopropyl amine), 800 mg (90%) of the title compound.

WORKUP

后处理

customafforded
customafter purification (SiO2: 10 DCM: 2 EtOAc: 2 Hexane: 0 to 0.125 isopropyl amine), 800 mg (90%) of the title compound