反应详情

Using coupling method A, 4-[2-amino-2-(4-pyridinyl)-ethoxymethyl]piperidine-1-carboxylic acid tert-butyl ester (233 mg, 0.69 mmol) and 3-chloroindole-6-carboxylic acid (149 mg, 0.76 mmol) afforded, after purification (SiO2: 10 DCM:2 EtOAc:2 Hexane:3 isopropyl amine), 118 mg (33%) of the title compound.

1. customafforded
2. customafter purification (SiO2: 10 DCM:2 EtOAc:2 Hexane:3 isopropyl amine), 118 mg (33%) of the title compound