HCID 54265004, compound → HCID 54123317, compound

HRID 324092Notes

Reaction equation

HRID 324092 reaction equation
[CH2:1]([O:3][C:4](=[O:17])[C:5]1[CH:10]=[C:9](I)[C:8]([O:12][CH2:13][O:14][CH3:15])=[C:7](Br)[CH:6]=1)[CH3:2].C(O[C:21](=O)[C:22]1[CH:27]=[C:26](Br)[C:25](OCOC)=[C:24](Br)[CH:23]=1)C>>[CH2:1]([O:3][C:4](=[O:17])[C:5]1[CH:10]=[C:9]([C:7]2[CH:8]=[CH:9][CH:10]=[C:5]([CH3:4])[CH:6]=2)[C:8]([O:12][CH2:13][O:14][CH3:15])=[C:7]([C:26]2[CH:25]=[CH:24][CH:23]=[C:22]([CH3:21])[CH:27]=2)[CH:6]=1)[CH3:2]

Participants

3

Reactant 2

HCID 54265004HCID 54265004, compoundHCID 54329281HCID 54329281, compound

Product 1

HCID 54123317HCID 54123317, compound

Procedure

3,5-Bis-(3-methylphenyl)-4-methoxymethoxybenzoic acid ethyl ester was prepared as a white solid (4.2 g, 30%) in a similar manner to Step 1 of Example 143 from a 2:1 mixture of 3-bromo-4-methoxymethoxy-5-iodobenzoic acid ethyl ester and 3,5-dibromo4-methoxymethoxybenzoic acid ethyl ester. 1H NMR (CDCl3) δ1.17 (t, J=8.18 Hz, 3H); 2.4 (s, 6H); 2.66 (s, 3H); 4.36 (quartet, J=8.18 Hz, 2H); 4.40 (s, 2H); 7.11-7.20 (m, 2H); 7.20-7.40 (m, 6H); 8.00 (s, 2H).

Sources & evidence

ORD record
ord-1d87be663886496dbc2e84df9bf60baa
Source dataset
uspto-grants-2001_04
Patent number
US06214877B1

Reaction notes

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