HuagongsheHuagongshe Chemistry Print Report · For research reference only
Anisole → HCID 69313093, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Anisole | HCID 7519 | — |
| Reactant | 4-{2-[(1H-indole-6-carbonyl)amino]-2-(4-fluoro-phenyl)ethoxymethyl}piperidine-1-carboxylic acid tert-butyl ester | HCID 69313231 | — |
| Product | HCID 69313093 | HCID 69313093 | 102.7% |
Reaction Steps
Using deprotection method B, but without addition of anisole, 4-{2-[(1H-indole-6-carbonyl)amino]-2-(4-fluoro-phenyl)ethoxymethyl}piperidine-1-carboxylic acid tert-butyl ester (1.6 g, 3.2 mmol) afforded 1.3 g (100%) of the title compound as a crude residue which was used without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07427632B2 |
| Source dataset | uspto-grants-2008_09 |
| ORD ID | ord-e32fcc12992c4947bebbd8c0f043d2a8 |
| Source note | uspto-grants-2008_09 |