Monobenzone → HCID 86756615, compound

Participants

Reaction Steps

{circle around (1)}: A mixture comprising 1.25 g of (S)-4-(1′-methylheptyloxy)benzoic acid, 1.0 g of 4-benzyloxyphenol, 1.03 g of DCC and 10 g of dichloromethane was stirred at room temperature for 30 minutes. Then, a catalytic amount of 4-N,N-dimethylaminopyridine was added to the mixture, and the mixture was further stirred at room temperature for 12 hours. After finishing the reaction, insoluble substances were filtered off, followed by distilling off dichloromethane from the filtrate under reduced pressure. The resultant residue was purified by means of silica gel column chromatography, whereby 2.21 g of (S)-4-[4′-(1″-methylheptyloxy)phenylcarbonyloxy)-1-benzyloxybenzene was obtained.

Provenance & Evidence