HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetone → HCID 10321712, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetone | HCID 180 | — |
| Reactant | HCID 9866338 | HCID 9866338 | — |
| Product | HCID 10321712 | HCID 10321712 | — |
Reaction Steps
Using alkylation method A, 3-chloro-N-[(R)-1-phenyl-2-(piperidin-4-ylmethoxy)ethyl]-1H-indole-6-carboxamide (8.97 mmol) and acetone (6.6 mL, 90 mmol) afforded, after purification (SiO2: 8:2:1 hexane:EtOAc:isopropylamine), 2.2 g (54%) of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07427632B2 |
| Source dataset | uspto-grants-2008_09 |
| ORD ID | ord-0165fa241aab4453aaf0068737beec5b |
| Source note | uspto-grants-2008_09 |