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HRID32425

反应详情

EQUATION

反应方程式

HRID 32425 的结构方程式

REACTANTS

反应物

2
结构：CC=O
HCID177

Acetaldehyde

C2H4O

结构：O=C(NC(COCC1CCNCC1)c1ccccc1Cl)c1ccc2c(Cl)c[nH]c2c1
HCID69307888

未命名化合物

PRODUCTS

生成物

1
结构：CCN1CCC(COCC(NC(=O)c2ccc3c(Cl)c[nH]c3c2)c2ccccc2Cl)CC1
HCID44444086

未命名化合物

PROCEDURE

实验过程

Using alkylation method A, 3-chloro-N-[1-(2-chloro-phenyl)-2-(piperidin-4-ylmethoxy)ethyl]-1H-indole-6-carboxamide (600 mg, 1.3 mmol) and acetaldehyde (0.4 mL, 6.7 mmol) afforded, after purification (SiO2: 10:10:1 hexane:EtOAc:isopropylamine) and recrystallization (acetonitrile), 275 mg (43%) of the title compound.

WORKUP

后处理

  1. customafforded
  2. customafter purification (SiO2: 10:10:1 hexane:EtOAc:isopropylamine) and recrystallization (acetonitrile), 275 mg (43%) of the title compound