Methanol → HCID 131722497, compound

Participants

Reaction Steps

Mix Boc-Ser(OBn)-Phe-Val-Gly(OMe), SEQ ID NO:23, (3.95 g, 6.45 mmol), 1 N sodium hydroxide (39 mL, 39 mmol), methanol (100 mL) and dioxane (60 mL). Stir at room temperature under a nitrogen atmosphere until hydrolysis is complete. Evaporate the solvent in vacuo and purify by silica gel chromatography (chloroform) to give Boc-Ser(OBn)-Phe-Val-Gly, SEQ ID NO:25, (3.32 g, 85.4%).

Provenance & Evidence