HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(3-Nitrophenyl)-1h-benzo[d]imidazole → 3-(1H-Benzo[d]imidazol-1-yl)aniline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(3-Nitrophenyl)-1h-benzo[d]imidazole | HCID 5328443 | — |
| Catalyst | Nickel | HCID 935 | — |
| Product | 3-(1H-Benzo[d]imidazol-1-yl)aniline | HCID 5328444 | 71% |
Reaction Steps
Reduction of 1-(3-nitrophenyl)benzimidazole (prepared by the method of M. A. Khan and J. B. Polya, J. Chem. Soc. (C), 1970:85-91) with Raney nickel as for Example 8, followed by chromatography on silica gel, eluting with EtOAc, gave Example 3 (71%), mp (EtOAc/hexane) 93-95° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06218388B1 |
| Source dataset | uspto-grants-2001_04 |
| ORD ID | ord-526a965c3d6c409eb40db84fb69340ea |
| Source note | uspto-grants-2001_04 |