Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 324385Generated: October 25, 2026

4-(Dimethylamino)Benzaldehyde → Ethyl 1,2,3,4-Tetrahydro-l-(4-Dimethylaminophenyl)-9H-Pyrido (3,4-b)Indole-3-Carboxylate

https://huagongshe.com/reaction/324385

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Dimethylamino)BenzaldehydeHCID 7479—
ReactantL-Tryptophan, ethyl esterHCID 81996—
ProductEthyl 1,2,3,4-Tetrahydro-l-(4-Dimethylaminophenyl)-9H-Pyrido (3,4-b)Indole-3-CarboxylateHCID 22677859—

Reaction Steps

The same method as employed in the preparation of Intermediates 1 and 2 but starting from racemic tryptophan ethyl ester and 4-dimethylaminobenzaldehyde gave the title compound as white crystals m.p.: 170° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06218400B1
Source datasetuspto-grants-2001_04
ORD IDord-6730f08bcdcc4db7bc759a20835b6fa7
Source noteuspto-grants-2001_04