Butyl isocyanate → HCID 69789369, compound

HRID 324387Notes

Reaction equation

HRID 324387 reaction equation
[C:1]1([C@H:7]2[C:12]3[NH:13][C:14]4[C:19]([C:11]=3[CH2:10][C@H:9]([C:20](OC)=[O:21])[NH:8]2)=[CH:18][CH:17]=[CH:16][CH:15]=4)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH2:24]([N:28]=[C:29]=[O:30])[CH2:25][CH2:26][CH3:27]>>[CH2:24]([N:28]1[C:20](=[O:21])[C@H:9]2[N:8]([C@@H:7]([C:1]3[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=3)[C:12]3[NH:13][C:14]4[CH:15]=[CH:16][CH:17]=[CH:18][C:19]=4[C:11]=3[CH2:10]2)[C:29]1=[O:30])[CH2:25][CH2:26][CH3:27]

Participants

3

Reactant 2

HCID 8110Butyl isocyanateHCID 736465HCID 736465, compound

Product 1

HCID 69789369HCID 69789369, compound

Procedure

The same method as employed in the preparation of Example 1 but starting from trans methyl 1,2,3,4-tetrahydro-1-phenyl-9H-pyrido[3,4-b]indole-3-carboxylate and butyl isocyanate gave after recrystallisation from 2-propanol, the title compound as white crystals m.p.: 240-243° C. Analysis for C23H23N3O2: Calculated: C,73.97;H,6.21;N,11.25;

Workup

  1. customThe same method as employed in the preparation of Example 1
  2. customgave
  3. customafter recrystallisation from 2-propanol

Sources & evidence

ORD record
ord-066acf684fc84d2491963241b5e5c4bb
Source dataset
uspto-grants-2001_04
Patent number
US06218400B1

Reaction notes

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