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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 324413Erstellt: 25. Oktober 2026

Methyl 3-(bromomethyl)benzoate → (+/-)-3-[[5-(7-Ethyl-2-methyl-4H-benzo[5,6]cyclohepta[1,2-d]oxazol-4-yl)-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl]methyl]benzoic acid, methyl ester

https://huagongshe.com/reaction/324413

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktMethyl 3-(bromomethyl)benzoateHCID 517981—
Edukt(+/-)-5-(7-Ethyl-2-methyl-4H-benzo[5,6]cyclohepta[1,2-d]oxazol-4-yl)-2,4(1H,3H)-pyrimidinedioneHCID 70113435—
Produkt(+/-)-3-[[5-(7-Ethyl-2-methyl-4H-benzo[5,6]cyclohepta[1,2-d]oxazol-4-yl)-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl]methyl]benzoic acid, methyl esterHCID 131722509—

Reaktionsschritte

The subtitle compound was prepared from the product of example 3 step (vii) (2. g) and 3-bromomethyl benzoic acid methyl ester (0.5 g) using the method of example 1 step (viii). Purification was by chromatography eluting with 60% ethyl acetate in toluene.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS06218376B1
Quelldatensatzuspto-grants-2001_04
ORD IDord-4eb3fca8a11941d2ab4eea3e461e6873
Quellennotizuspto-grants-2001_04