Methyl iodide → HCID 70112109, compound

HRID 324433Notes

Reaction equation

HRID 324433 reaction equation
[CH3:1][C:2]1[O:3][C:4]2[CH:11]([C:12]3[C:13](=[O:19])[NH:14][C:15](=[O:18])[NH:16][CH:17]=3)[C:10]3[CH:20]=[CH:21][C:22]([CH3:24])=[CH:23][C:9]=3[CH:8]=[CH:7][C:5]=2[N:6]=1.I[CH3:26]>>[CH3:26][N:16]1[CH:17]=[C:12]([CH:11]2[C:4]3[O:3][C:2]([CH3:1])=[N:6][C:5]=3[CH:7]=[CH:8][C:9]3[CH:23]=[C:22]([CH3:24])[CH:21]=[CH:20][C:10]2=3)[C:13](=[O:19])[NH:14][C:15]1=[O:18]

Participants

3

Reactant 2

HCID 6328Methyl iodideHCID 70227863HCID 70227863, compound

Product 1

HCID 70112109HCID 70112109, compound

Procedure

The title compound was prepared from the product of example 13 step (vii) (0.66 g) and iodomethane (0.49 ml) according to the method of example 1 step (viii). Purification was by chromatography eluting with 5% methanol in dichloromethane.

Workup

  1. customPurification
  2. washeluting with 5% methanol in dichloromethane

Sources & evidence

ORD record
ord-57687e670963475a9c3bc134523c71d3
Source dataset
uspto-grants-2001_04
Patent number
US06218376B1

Reaction notes

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