HCID 70113184, compound → HCID 70114562, compound

HRID 324434Notes

Reaction equation

HRID 324434 reaction equation
CC(C)([O:4][C:5]1[N:10]=[C:9]([O:11]C(C)(C)C)[C:8]([C:16]2([OH:32])[C:25]3[S:24][C:23]([CH3:26])=[N:22][C:21]=3[CH2:20][CH2:19][C:18]3[CH:27]=[C:28]([CH3:31])[CH:29]=[CH:30][C:17]2=3)=[CH:7][N:6]=1)C>C(O)(=O)C>[OH:32][C:16]1([C:8]2[C:9](=[O:11])[NH:10][C:5](=[O:4])[NH:6][CH:7]=2)[C:25]2[S:24][C:23]([CH3:26])=[N:22][C:21]=2[CH2:20][CH2:19][C:18]2[CH:27]=[C:28]([CH3:31])[CH:29]=[CH:30][C:17]1=2

Participants

3

Reactant 1

HCID 70113184HCID 70113184, compound

Product 1

HCID 70114562HCID 70114562, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

A solution of the product from step (iv) in acetic acid was stirred overnight. The solvent was removed under reduced pressure and the residue purified by chromatography eluting with 5-6% methanol in dichloromethane.

Workup

  1. customThe solvent was removed under reduced pressure
  2. customthe residue purified by chromatography
  3. washeluting with 5-6% methanol in dichloromethane

Sources & evidence

ORD record
ord-f3555bdcc78d4a369184b9c559134703
Source dataset
uspto-grants-2001_04
Patent number
US06218376B1

Reaction notes

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