Lawesson's reagent → HCID 9884067, compound

HRID 324437Notes

Reaction equation

HRID 324437 reaction equation
[CH3:1][C:2]1[CH:24]=[CH:23][C:5]2[CH:6]([C:15]3[C:16](=O)[NH:17][C:18](=[O:21])[NH:19][CH:20]=3)[C:7]3[C:8]([CH:13]=[CH:14][C:4]=2[CH:3]=1)=[N:9][CH:10]=[CH:11][CH:12]=3.COC1C=CC(P2(SP(C3C=CC(OC)=CC=3)(=S)S2)=[S:34])=CC=1>>[CH3:1][C:2]1[CH:24]=[CH:23][C:5]2[CH:6]([C:15]3[C:16](=[S:34])[NH:17][C:18](=[O:21])[NH:19][CH:20]=3)[C:7]3[C:8]([CH:13]=[CH:14][C:4]=2[CH:3]=1)=[N:9][CH:10]=[CH:11][CH:12]=3

Participants

3

Reactant 2

HCID 87949Lawesson's reagentHCID 22003606HCID 22003606, compound

Product 1

HCID 9884067HCID 9884067, compound

Procedure

The title compound was prepared from the product of step (iv) (0.53 g) and Lawesson's reagent (0.675 g) according to the method of example 2 step (ii). Purification was by chromatography eluting with 50% acetone in iso-hexane followed by trituration with acetonitrile.

Workup

  1. customPurification
  2. washeluting with 50% acetone in iso-hexane

Sources & evidence

ORD record
ord-a02daf1da8fa46109b6a66dddc120eca
Source dataset
uspto-grants-2001_04
Patent number
US06218376B1

Reaction notes

Loading…