HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetone → 3-Chloro-N-[1-butyl-2-(1-isopropylpiperidin-4-ylmethoxy)-ethyl]-1H-indole-6-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetone | HCID 180 | — |
| Reactant | 3-chloro-N-[1-butyl-2-(piperidin-4-ylmethoxy)ethyl]-1H-indole-6-carboxamide | HCID 69307987 | — |
| Product | 3-Chloro-N-[1-butyl-2-(1-isopropylpiperidin-4-ylmethoxy)-ethyl]-1H-indole-6-carboxamide | HCID 69310447 | — |
Reaction Steps
Using alkylation method A, 3-chloro-N-[1-butyl-2-(piperidin-4-ylmethoxy)ethyl]-1H-indole-6-carboxamide (0.18 mmol) and acetone (1 mL, 14 mmol) afforded, after SCX purification, 60 mg (70%) of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07427632B2 |
| Source dataset | uspto-grants-2008_09 |
| ORD ID | ord-313a5cc59bc441b69bc97f80570a8a42 |
| Source note | uspto-grants-2008_09 |