反应详情

To a solution of the product from step (x) (3.1 g) in dry dimethylsulphoxide (30 ml) and dry 1,4-dioxane (90 ml) was added sodium borohydride (0.7 g). After stirring at room temperature for 24 h the reaction mixture was quenched with water and extracted with ethyl acetate. The organic layer was washed with saturated sodium bicarbonate solution, then brine. The organic layer was collected and dried over magnesium sulphate and solvent removed under reduced pressure to leave a pale yellow gum.

1. customwas quenched with water
2. extractionextracted with ethyl acetate
3. washThe organic layer was washed with saturated sodium bicarbonate solution
4. customThe organic layer was collected
5. dry with materialdried over magnesium sulphate and solvent
6. customremoved under reduced pressure
7. customto leave a pale yellow gum