Aluminum(III) Chloride → HCID 22003661, compound

HRID 324489Notes

Reaction equation

HRID 324489 reaction equation
[Cl-].[Al+3].[Cl-].[Cl-].[Cl:5][C:6]1[S:7][C:8]([CH2:14][CH2:15][C:16]2[CH:21]=[CH:20][CH:19]=[C:18]([Cl:22])[CH:17]=2)=[C:9]([C:11](Cl)=[O:12])[N:10]=1>ClCCl>[Cl:5][C:6]1[S:7][C:8]2[CH2:14][CH2:15][C:16]3[CH:17]=[C:18]([Cl:22])[CH:19]=[CH:20][C:21]=3[C:11](=[O:12])[C:9]=2[N:10]=1

Participants

4

Reactant 2

HCID 6451240Aluminum(III) ChlorideHCID 54563767HCID 54563767, compound

Product 1

HCID 22003661HCID 22003661, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

Aluminium chloride (5.3 g) was added to a solution of the product from step (iv) in dichloromethane (30 ml) at room temperature. After 3 h the mixture was poured onto 2M HCl/ice and the product extracted into ethyl acetate. The organic phase was collected, dried, (MgSO4) and solvent evaporated under reduced pressure to leave a brown solid. This was triturated with isohexane/ethyl acetate and filtered to leave the subtitle product as a beige solid.

Workup

  1. extractionthe product extracted into ethyl acetate
  2. customThe organic phase was collected
  3. customdried
  4. custom(MgSO4) and solvent evaporated under reduced pressure
  5. customto leave a brown solid
  6. customThis was triturated with isohexane/ethyl acetate
  7. filtrationfiltered

Sources & evidence

ORD record
ord-e1b36dad88244ec0b5f580ecdf2867d8
Source dataset
uspto-grants-2001_04
Patent number
US06218376B1

Reaction notes

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