HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Chloro-1H-indole-6-carboxylic acid → HCID 69309695, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Chloro-1H-indole-6-carboxylic acid | HCID 15543042 | — |
| Reactant | 4-(4-Isopropylpiperazin-1-yl)-1-phenylbutylamine | HCID 63322063 | — |
| Product | HCID 69309695 | HCID 69309695 | — |
Reaction Steps
Using coupling method A, crude 4-(4-isopropylpiperazin-1-yl)-1-phenylbutylamine (530 mg, 1.9 mmol) and 3-chloro-indole-6-carboxylic acid (376 mg, 1.9 mmol) afforded, after purification (SiO2: 10:10:1 hexane:EtOAc:isopropyl-amine), 184 mg (21%) of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07427632B2 |
| Source dataset | uspto-grants-2008_09 |
| ORD ID | ord-ff77d1fd54164d84be3dbe4bf6c6783f |
| Source note | uspto-grants-2008_09 |