Nitric Acid → HCID 178526806, compound

HRID 324682Notes

Reaction equation

HRID 324682 reaction equation
[N:1]1[CH:6]=[CH:5][C:4](=[O:7])[CH2:3][CH:2]=1.[N+:8]([O-])([OH:10])=[O:9].S(=O)(=O)(O)O>>[OH:7][C:4]1[CH:3]=[CH:2][N:1]=[CH:6][C:5]=1[N+:8]([O-:10])=[O:9]

Participants

4

Reactant 3

HCID 944Nitric AcidHCID 1118Sulfuric AcidHCID 17984897Piridin-4-one

Product 1

HCID 178526806HCID 178526806, compound

Conditions

Temperature
100 °C

Procedure

4-Hydroxy-3-nitropyridine was prepared by addition of 4-pyridone (50 g, 0.532M) to a mixture of fuming nitric acid and sulfuric acid. The resulting solution was heated for 1 hour at 100° C. The solution was cooled and poured into 500 mL of ice water and the desired product was obtained as a solid. (mp. 280° C.)

Workup

  1. temperatureThe solution was cooled

Sources & evidence

ORD record
ord-03a3bcf3a2f6459081fce41f6943813e
Source dataset
uspto-grants-2001_04
Patent number
US06218539B1

Reaction notes

Loading…