HCID 54057735, compound → HCID 22005216, compound

HRID 324797Notes

Reaction equation

HRID 324797 reaction equation
[CH3:1][C:2]1[C:7]([CH2:8][OH:9])=[C:6]([C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)[C:5]([CH:16]=[CH:17][CH2:18][CH2:19][CH3:20])=[C:4]([CH3:21])[N:3]=1>C(OCC)(=O)C.CCCCCC>[CH3:1][C:2]1[C:7]([CH2:8][OH:9])=[C:6]([C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)[C:5]([CH2:16][CH2:17][CH2:18][CH2:19][CH3:20])=[C:4]([CH3:21])[N:3]=1

Participants

3

Reactant 1

HCID 54057735HCID 54057735, compound

Product 1

HCID 22005216HCID 22005216, compound

Reagents, catalysts & solvents 1

HCID 21226206Ethyl acetate hexaneSolvent

Procedure

The title compound was prepared from 2,6dimethyl-3-hydroxymethyl-4-phenyl-5-(1-pentenyl)pyridine (Example 3) according to the procedure described in Example 1, Step H. 1H NMR (300 MHz, CDCl3): δ7.42 (m, 3 H), 7.15 (m, 2 H), 4.33 (s, 2 H), 2.65 (s, 3 H), 2.56 (s, 3 H), 2.27 (m, 2 H), 1.29 (m, 2 H), 1.11 (m, 4 H), 0.76 (t, J =7 Hz, 3 H). EI-MS: calculated for (C19H25NO) 283, found 283 (M+). Anal. calculated for C19H25NO: C, 80.52; H, 8.89; N, 4.94. Found: C, 80.39; H, 8.85; N, 4.85. mp 99-100° C. Rf=0.3 (90% ethyl acetate/hexane).

Sources & evidence

ORD record
ord-75adfc06a0a04fd3b5477a0aa1ce9b52
Source dataset
uspto-grants-2001_04
Patent number
US06218431B1

Reaction notes

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