HCID 53752501, compound → HCID 22004900, compound

Participants

Reaction Steps

The title compound was prepared from 2,6-diisopropyl-3-hydroxymethyl-4-phenyl-5-(1-butenyl)pyridine (Example 13) according to the procedure described in Example 1, Step H. 1H NMR (300 MHz, CDCl3): δ7.41 (m, 3 H), 7.17 (m, 2 H), 4.33 (s, 2 H), (sept, J=6.6 Hz, 1 H), 3.24 (sept, J=6.6 Hz, 1 H), 2.28 (m, 2 H), 1.33 (d, J=6.6 Hz, 6 H), 1.31 (d, J=6.6 Hz, 6 H), 1.28 (m, 2 H), 1.14 (m, 3 H), 0.71 (t, J=7 Hz, 3 H). FAB-MS: calculated for (C22H31NO) 325, found 326 (M+H). Anal. Calcd for C22H31NO: C, 81.18; H, 9.60; N, 4.30. Found: C, 81.28; H, 9.87; N, 4.07. mp 83-84° C. Rf=0.4 (20% ethyl acetate/hexane).

Provenance & Evidence