Isocyanate → HCID 178441173, compound

HRID 32485Notes

Reaction equation

HRID 32485 reaction equation
C1(O[C:8](=[O:19])[NH:9][C:10]2[CH:14]=[C:13]([C:15]([CH3:18])([CH3:17])[CH3:16])[O:12][N:11]=2)C=CC=CC=1.[N-]=C=O.[NH2:23][C:24]1[N:29]([C:30]2[CH:35]=[CH:34][CH:33]=[C:32]([NH2:36])[CH:31]=2)[CH2:28][N:27]=[C:26]2[O:37][CH:38]=[CH:39][C:25]=12>>[NH2:23][C:24]1[N:29]([C:30]2[CH:35]=[CH:34][CH:33]=[C:32]([NH:36][C:8]([NH:9][C:10]3[CH:14]=[C:13]([C:15]([CH3:16])([CH3:17])[CH3:18])[O:12][N:11]=3)=[O:19])[CH:31]=2)[CH2:28][N:27]=[C:26]2[O:37][CH:38]=[CH:39][C:25]=12

Participants

4

Reactant 3

HCID 105034IsocyanateHCID 13489605Phenyl 5-tert-butylisoxazol-3-ylcarbamateHCID 178507142HCID 178507142, compound

Product 1

HCID 178441173HCID 178441173, compound

Procedure

The compound was prepared following the procedure described in Example 232(b), using (5-t-butyl-isoxazol-3-yl)-carbamic acid phenyl ester as the isocyanate of choice, and 4-Amino-3-(3-aminophenyl)furo[2,3-d]pyrimidine (10) as the diamine of choice. MS(ES) m/e 393 [M+H]+.

Workup

  1. customThe compound was prepared

Sources & evidence

ORD record
ord-bfdb7b1df3924e578a391468f3169498
Source dataset
uspto-grants-2008_09
Patent number
US07427623B2

Reaction notes

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