HCID 54345918, compound → HCID 22005133, compound

Participants

Reaction Steps

The title compound was prepared from 2,6-diisopropyl-3-hydroxymethyl-4-(3-benzyloxyphenyl)-5-(pent-1-enyl)pyridine (Example 152) by the procedure described in Example 126. 1H NMR (300 MHz, CDCl3): δ 0.78 (t, J=7.0 Hz, 3 H), 1.28 (m, 18 H), 2.28 (m, 2 H), 3.22 (m, 1 H), 3.39 (m, 1 H), 4.34 (m, 2 H), 5.52 (s, 1 H), 6.63 (m, 1 H), 6.71 (d, J=8.0 Hz, 1 H), 6.81 (m, 1 H), 7.26 (m, 1 H). FAB-MS: calculated for C23H33NO2 356; found 357 (M+H, 100%). Elemental analysis: calculated for C23H33NO2: C 77.70; H 9.36; N 3.94, found: C 76.51; H 9.49; N 3.85. Rf 0.21 (10% ethyl acetate/n-hexane). mp 121-122° C.

Provenance & Evidence