HuagongsheHuagongshe Chemistry Print Report · For research reference only
Butanedione → (Z)-7,9-dihydro-2,3-dimethyl-9-[(3-methoxy-1H-pyrrol-2-yl)methylene]-8H-pyrrolo-[3,2-f]quinoxalin-8-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Butanedione | HCID 650 | — |
| Reactant | HCID 15512603 | HCID 15512603 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | (Z)-7,9-dihydro-2,3-dimethyl-9-[(3-methoxy-1H-pyrrol-2-yl)methylene]-8H-pyrrolo-[3,2-f]quinoxalin-8-one | HCID 9905146 | 100% |
Reaction Steps
Using Method A above, (Z)-4,5-diamino-1,3-dihydro-3-[(3-methoxy-1H-pyrrol-2-yl)methylene]-2H-indol-2-one (60 mg, 0.22 mmol) (Starting Material 5) was condensed with 2,3-butanedione (135 μL) (Aldrich) in ethanol (3 ml) at reflux to give (Z)-7,9-dihydro-2,3-dimethyl-9-[(3-methoxy-1H-pyrrol-2-yl)methylene]-8H-pyrrolo-[3,2-f]quinoxalin-8-one in 100% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06221867B1 |
| Source dataset | uspto-grants-2001_04 |
| ORD ID | ord-fbc30e3964074ba392db3c98ca5b258c |
| Source note | uspto-grants-2001_04 |