HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 22001500, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Benzylamine | HCID 7504 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | HCID 22001501 | HCID 22001501 | — |
| Solvent | Dimethylacetamide | HCID 31374 | — |
| Product | HCID 22001500 | HCID 22001500 | 27.2% |
Reaction Steps
A solution of 100 mg of 4-fluoro-N-indan-1-yl-3-(3-methylbutylsulfamoyl)benzamide (Example 41), 29 mg of benzylamine, and 100 mg of potassium carbonate in 4 ml of N,N-dimethylacetamide was heated to 100° C. for 6 h. After the addition of water, extraction with EA, and chromatographic separation, 33 mg of 4-benzylamino-N-indan-1-yl-3-(3-methylbutylsulfamoyl)benzamide were obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06221866B1 |
| Source dataset | uspto-grants-2001_04 |
| ORD ID | ord-a1ed8d8670d047cfb7c4e3dc3859279e |
| Source note | uspto-grants-2001_04 |